Apo-Semaglutide price in Canada, by pharmacy and province
Apo-Semaglutide runs $92 to $123 a month in Ontario as a cash price, depending on strength and pharmacy. Cheapest counter right now is Costco Pharmacy at $92 for the 0.25 mg starting dose. It is already the generic, so brand-to-generic savings cards have nothing to cover.
Every Apo-Semaglutide strength in Ontario
| Strength | Cheapest pharmacy | Drug price | Cash total | With savings card | Per dose | Priciest |
|---|---|---|---|---|---|---|
| 0.25 mg Starting dose 1 pen, 4 weekly doses | Costco Pharmacy Membership not required to use the pharmacy | $88 | $92 | Already generic | $23 | $123 |
| 0.5 mg 1 pen, 4 weekly doses | Costco Pharmacy Membership not required to use the pharmacy | $88 | $92 | Already generic | $23 | $123 |
| 1 mg 1 pen, 4 weekly doses | Costco Pharmacy Membership not required to use the pharmacy | $88 | $92 | Already generic | $23 | $123 |
| 2 mg 1 pen, 4 weekly doses | Costco Pharmacy Membership not required to use the pharmacy | $88 | $92 | Already generic | $23 | $123 |
Savings-card figures come from each programme’s published terms and vary by eligibility, plan and pen strength. One pen contains four weekly doses. Totals include the pharmacy’s dispensing fee.
Apo-Semaglutide across the provinces
| Province | Cheapest pharmacy | Cash total | With savings card | vs cheapest province | Checked |
|---|---|---|---|---|---|
| Ontario You | Costco Pharmacy | $92 | Already generic | cheapest | Audited Aug 2026 |
| Costco Pharmacy | $92 | Already generic | +$0 | Audited Aug 2026 | |
| Costco Pharmacy | $92 | Already generic | +$0 | Audited Aug 2026 | |
| Costco Pharmacy | $92 | Already generic | +$0 | Audited Aug 2026 | |
| Costco Pharmacy | $92 | Already generic | +$0 | Audited Aug 2026 | |
| Costco Pharmacy | $92 | Already generic | +$0 | Audited Aug 2026 | |
| CanadaDrugsOnline | $97 | Already generic | +$5 | Estimated | |
| CanadaDrugsOnline | $98 | Already generic | +$6 | Estimated | |
| CanadaDrugsOnline | $98 | Already generic | +$6 | Estimated | |
| CanadaDrugsOnline | $101 | Already generic | +$9 | Estimated |
The details, if you want them
Why does the same pen cost more at one chain than another?
Every pharmacy sets its own markup on the drug and its own dispensing fee on top. In our data Costco Pharmacy is consistently lowest for Apo-Semaglutide, and the gap to the priciest chain we track is $31 a month on the starting dose alone. Nothing about the medication differs.
Does the province I live in change the price?
Yes, by a few percent. Provincial rules on pharmacist fees and which chains operate differ, so Ontario is currently the cheapest province we track for Apo-Semaglutide and Quebec the most expensive, a $9 monthly difference. Two Western-Canada-only chains also drop out of the comparison in central and Atlantic provinces.
Should I buy a higher strength and split it?
We publish prices, not dosing advice, and pen strengths are not interchangeable. The per-dose column exists so you can see how the cost curve moves as you titrate, not as a suggestion to redose. Any change to how you take a GLP-1 is a conversation with your prescriber.
How are these numbers checked?
Every row says. Audited rows come from a published August 2026 retail phone audit; Estimated rows are modelled from list pricing and should be confirmed with the pharmacy; Verified rows mean we phoned that counter on the date shown. The methodology page explains each tier.
Every row on this page carries its own label: Audited, Estimated or Verified. Nothing here is a manufacturer list price presented as a counter price. The methodology sets out each tier.